| 双酚A和酞酸酯对鱼类的内分泌干扰效应和繁殖毒性的研究进展 |
| Research Progress of Endocrine-disrupting Effects and Reproductive Toxicity of Bisphenol A and Phthalic Acid Esters on Fish |
| 投稿时间：2015-08-28 修订日期：2017-03-08 |
| DOI：10.15928/j.1674-3075.2017.06.001 |
| 中文关键词:双酚A 酞酸酯 内分泌干扰 生殖毒性 鱼类 |
| 英文关键词:Bisphenol A (BPA) Phthalate Acid Esters (PAEs) endocrine disruption reproductive toxicity fish |
| 基金项目:中国长江三峡集团公司科研项目（0799555）“保护区河道水质变化及其对鱼类影响研究” |
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| 中文摘要: |
| 环境雌激素作为一类内分泌干扰物进入人和动物体内后能干扰机体内分泌系统的正常功能，通过多种机制表现出拟天然雌激素或者抗天然雄激素的作用。双酚A（bisphenol A, BPA）和酞酸酯（也称作邻苯二甲酸酯，Phthalic Acid Esters, PAEs）是具有雌激素类活性的环境内分泌干扰物，广泛存在于水环境中，并对水生动物，特别是鱼类的安全造成潜在威胁。本文总结了目前BPA和PAEs对鱼类毒性效应的研究成果，特别是内分泌干扰作用和生殖毒性，为评估这两类环境污染物对鱼类的影响提供参考。 |
| 英文摘要: |
| Environmental estrogens, a group of endocrine disruptors, could enter human bodies and animals, and show estrogenic or anti-androgenic activities by diverse mechanisms, consequently disrupting their normal functions of the endocrine systems. Bisphenol A (BPA) and phthalate acid esters (PAEs) are endocrine-disrupting chemicals with estrogenic activities and widely present in aquatic environment. They have the potential threat on the aquatic animals especially on fish. In the present study, we summarized recent research progress regarding toxic effect of BPA and PAE to fish, particularly relating to endocrine-disrupting and reproductive toxicity. BPA and PAE pollution could disrupt endocrine of fish, destroy reproductive capacity and early stage of gondola development, affect the sexual differentiation and lead to the structural differentiation of gonadal tissue. This paper would provide a reference to the risk assessment of the two environmental contaminants on fish. |
| 赵 荧,李 媛,陈永柏.2017.双酚A和酞酸酯对鱼类的内分泌干扰效应和繁殖毒性的研究进展[J].水生态学杂志,38(6):1-10. |
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