| 离子液体［Ｃ８Ｍｉｍ］Ｃｌ对泥鳅毒性效应的研究 |
| A Study on the Toxicity Effect of [C8 Mim]Cl to Misgurnus anguillicaudatus |
| 投稿时间：2012-06-11 修订日期：2012-06-11 |
| DOI： |
| 中文关键词:泥鳅 离子液体 毒性 |
| 英文关键词:Misgurnus anguillicaudatus [C8 Mim]Cl toxicity |
| 基金项目:国家自然科学基金(3071666);河南师范大学博士基金(No.01046500120) |
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| 中文摘要: |
| 以泥鳅(Misgurnus anguillicaudatus)为受试动物,采用急性毒性、遗传毒性及生理毒性试验,研究了[C8Mim]Cl对生物体的毒性效应。结果表明,[C8Mim]Cl对泥鳅有一定的毒性,其对泥鳅24 h、48 h的LC50分别为324.13 mg/L、262.77mg/L,安全浓度为51.80 mg/L;各处理组的微核率均高于对照组(P<0.05),且随着处理浓度的升高和时间的推移,红细胞微核率都有明显的升高;处理组血清中的谷丙转氨酶(GPT)和谷草转氨酶(GOT)活力均明显高于对照组(P<0.05),且随离子液浓度升高以及时间的推移而增高;[C8Mim]Cl对泥鳅有显著的毒性作用。 |
| 英文摘要: |
| In this study，the toxicity effect of [C8 Mim]Cl to loach (Misgurnus anguillicaudatus)was studied using the methods of acute toxicity test，genetic toxicity test，and physical toxicity test. The results of above tests showed that :[C8 Mim]Cl had a certain toxicity effect to loach，and the LC50 of 24 h，48 h were 324. 13 mg/L,262.77 mg/L, and its safe concentration was 51.80 mg/L; the micronucleus rates of treatment groups were all higher than the control group，and there were significant differences(P<0.05)between the treatment groups and control group; the GPT and GOT activities of blood serum in the treatment groups were significantly higher than the control group(P<0.05)，and the activities of GPT and GOT became more and more higher with the increase of treating concentrations and treating time of ion liquid. In conclusion: [C8 Mim]Cl had a significant toxicity effect on M. anguillicaudatus). |
| 燕帅国,南平,韩晨露,杜启艳,常重杰.2012.离子液体［Ｃ８Ｍｉｍ］Ｃｌ对泥鳅毒性效应的研究[J].水生态学杂志,33(5):119-122. |
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